My experience with this thing:
My zoom level is normally set to x2, and like with cheatfreak, it can't go higher. (Probably for the same reason but i don't know my resolution.)
So i recently checked this to see if it would happen to me. It did, but not nearly as frequently as 50% of the time. Unless he meant it had 50% chance of happening (Monte Carlo fallacy and all that), i'd say it's more like 10% or less, for me at least. I never had this problem when resetting after playing a level. And regarding that changing the zoom level thing, for me it happens regardless of how much you spam Ctrl + Z.
Also, cheatfreak, like Sergio said, clicking one of the menu buttons fixes the zoom thing. I think clicking a Play button that's slightly higher up would be preferrable over hammering that poor F2 button.