I've had a little luck getting Saira to run in WINE.
It's not all happy times though.
http://img.photobucket.com/albums/v329/LightningEagle/Screenshot.pngIf anyone know how to fix such a black thingie... please do tell.
I'll report back with any progress I make.
EDIT: maybe I should mention. Up to that point everything has run very nice, apart from the weird black area.
EDIT2: hmm...
(EDIT3:) some fonts are messed up.
@Nifflas: what fonts are used in the game?
EDIT4:
* The menu box opens just fine and other boxes also.
* Text in menu works fine.
* Photos doesn't show up. They're there, they're just all black.
* It's the small text, for instance where you mount the the parts in the teleporter. The text in that box is messed.
* When looking at the window and the black frame (see picture), the game-image is pushed down the height of the upper black bar and the right side is covered by the bar in that position.
* Puzzles appear to work fine. At least the two first ones do.
EDIT5:
Application crashed when I tried to run the Device Solver with a puzzle.