Certainly. Make an image of a vignette border 600 by 240 pixels. Use this code:
[Custom Object 1]
Image=Vignette.png
Tile Width=600
Tile Height=240
Offset X=-288
Offset Y=-108
Finally, place object the object in the bottom-right corner of layer 7. This will put it in front of everything else including other objects on layer 7.
There is a problem with objects appearing briefly after entering a screens. This is most noticeable when shifting to duplicate screens. The best remedy is to use a KS mod. KS Ex and KS+ both render objects on the first pass.
Here's an example vignette image I made to make sure I had the offsets correct